Senior Bioinformatics Scientist
Veracyte
Apply by Voice
Have a quick 6-10 minute voice conversation to share your background and learn about this role. No resume needed.
About this role
•
Job Detail | Veracyte
•••••••••••••••
•
••
•••**
Mobile navigation**Back
• TestsTests
•
For Providers
•
For Patients
Tests for ProvidersClinical Tests
AfirmaGenomic Sequencing Classifier
DecipherBladder Genomic Classifier
DecipherProstate Genomic Classifier
ProsignaBreast Risk ofRecurrence TestDiscover
Provider Resource Center
Scientific Publications
Veracyte Diagnostics Platform
Clinical StudiesConnect With Us
Ordering Portal
Contact UsTests for PatientsCancer Tests
AfirmaThyroid Nodule Test
DecipherBladder Cancer Test
DecipherProstate Cancer Test
ProsignaBreast Cancer TestLearn
Patient Resource Center
Patient Video Stories
Frequently Asked QuestionsNeed Help?
Payment Portal
Contact Us• **ResourcesResources
•
For Providers
•
For Patients
Resources for ProvidersResource Centers
Afirma Thyroid Resources
Decipher Bladder Resources
Decipher Prostate Resources
Prosigna Breast Resources
View All → Explore
Scientific Publications
Frequently Asked Questions
Video Gallery
Document Library
Cancer Diagnostic LabsConnect With Us
Ordering Portal
Contact UsResources for PatientsResource Centers
Afirma Thyroid Resources
Decipher Bladder Resources
Decipher Prostate Resources
Prosigna Breast Resources
View All → Explore
Patient Video Stories
Frequently Asked QuestionsConnect With Us
Payment Portal
Contact Us• **InnovationInnovationTechnology
Veracyte Diagnostics Platform
Clinical Studies
Technology & Pipeline
TrueMRD Platform
Cancer Diagnostic LabsResearch Use Only
Afirma GRID
Decipher GRID• **CompanyCompanyAbout Us
About Veracyte
Leadership
Careers
Working at VeracyteNews & Events
Events & Webinars
Press Releases
In the News
BlogConnect
Contact Us• **InvestorsInvestorsWelcome
Overview
Press Releases
Events & PresentationsFinancials
SEC Filings
Quarterly Results
Annual Reports
Stock Information
Analyst CoverageGovernance
Governance Overview
Board of Directors
Committee Composition
Leadership
ESG InformationInvestor Resources
Investor FAQs
Information Request
Email AlertsContact Us Portals
SearchSearch
• Patient Payment Portal• Provider Portal• Tests
For Providers
For PatientsClinical Tests
AfirmaGenomic Sequencing Classifier
DecipherBladder Genomic Classifier
DecipherProstate Genomic Classifier
ProsignaBreast Risk ofRecurrence TestDiscover
Provider Resource Center
Scientific Publications
Veracyte Diagnostics Platform
Clinical StudiesConnect With Us
Ordering Portal
Contact UsCancer Tests
AfirmaThyroid Nodule Test
DecipherBladder Cancer Test
DecipherProstate Cancer Test
ProsignaBreast Cancer TestLearn
Patient Resource Center
Patient Video Stories
Frequently Asked QuestionsNeed Help?
Payment Portal
Contact Us• Resources**
For Providers
For PatientsResource Centers
Afirma Thyroid Resources
Decipher Bladder Resources
Decipher Prostate Resources
Prosigna Breast Resources
View All → Explore
Scientific Publications
Frequently Asked Questions
Video Gallery
Document Library
Cancer Diagnostic LabsConnect With Us
Ordering Portal
Contact UsResource Centers
Afirma Thyroid Resources
Decipher Bladder Resources
Decipher Prostate Resources
Prosigna Breast Resources
View All → Explore
Patient Video Stories
Frequently Asked QuestionsConnect With Us
Payment Portal
Contact Us• InnovationTechnology
Veracyte Diagnostics Platform
Clinical Studies
Technology & Pipeline
TrueMRD Platform
Cancer Diagnostic LabsResearch Use Only
Afirma GRID
Decipher GRID• CompanyAbout Us
About Veracyte
Leadership
Careers
Working at VeracyteNews & Events
Events & Webinars
Press Releases
In the News
BlogConnect
Contact Us• InvestorsWelcome
Overview
Press Releases
Events & PresentationsFinancials
SEC Filings
Quarterly Results
Annual Reports
Stock Information
Analyst CoverageGovernance
Governance Overview
Board of Directors
Committee Composition
Leadership
ESG InformationInvestor Resources
Investor FAQs
Information Request
Email Alerts**
•
Careers•
Job DetailSenior Bioinformatics ScientistRemote | San Diego, California, United States | South San Francisco, California, United StatesResearch & Development (R&D)At Veracyte, we offer exciting career opportunities for those interested in joining a pioneering team that is committed to transforming cancer care for patients across the globe. Working at Veracyte enables our employees to not only make a meaningful impact on the lives of patients, but to also learn and grow within a purpose driven environment. This is what we call the Veracyte way – it’s about how we work together, guided by our values, to give clinicians the insights they need to help patients make life-changing decisions.Our Values:• We Seek A Better Way: We innovate boldly, learn from our setbacks, and are resilient in our pursuit to transform cancer care• We Make It Happen: We act with urgency, commit to quality, and bring fun to our hard work• We Are Stronger Together: We collaborate openly, seek to understand, and celebrate our wins• We Care Deeply: We embrace our differences, do the right thing, and encourage each otherThe Position:We are seeking a highly experienced and motivated Senior Bioinformatics Scientist to drive the design, and development of next‑generation minimal residual disease (MRD) laboratory‑developed tests (LDTs). This senior, independent scientist position is responsible for contributing to assay concepts, driving analytical development and validation, and partnering closely with wet‑lab, clinical, quality, regulatory, and software teams to deliver robust, clinically actionable MRD diagnostics for multiple indications.The ideal candidate brings expertise in NGS‑based oncology assays, strong understanding of ctDNA biology and a proven track record of industry assay development under design control. This individual will lead technical execution of key scientific efforts, owning assay bioinformatics from concept through analytical validation and launch.KEY RESPONSIBILITIES:Scientific & Technical Expertise• Contribute to bioinformatics strategy for MRD assay design, development, optimization, and lifecycle management for LDTs developed under CAP/CLIA quality systems.• Lead and contribute to study design, data analysis, performance characterization, and decision‑making throughout development.• Apply deep domain knowledge in cancer genomics, ctDNA biology, and NGS technologies to inform assay architecture, variant detection strategies, and error suppression approaches in collaboration with our data science and modeling teams.Assay Development & Validation• Design and execute analytical studies to evaluate assay performance, including accuracy, limit of detection, and reproducibility, in collaboration with wet‑lab and biostatistics partners.• Develop, validate, and maintain scalable, production‑ready bioinformatics pipelines for MRD analysis, including QC, variant calling, MRD calling logic, and reporting.• Lead benchmarking and optimization of computational methods, including background error modeling, and longitudinal MRD tracking.• Ensure compliance with standards (CAP/CLIA, FDA, IVDR) throughout the bioinformatics development lifecycle, including rigorous testing and documentation.Cross‑Functional Collaboration• Partner closely with molecular biology, assay development, QA/RA, clinical, and software engineering teams to ensure bioinformatics solutions are aligned with assay design, regulatory expectations, and operational constraints.• Contribute to regulatory submissions and audits by providing technical documentation and validation report, and responses to audits or regulatory inquiries.Mentorship & Influence• Provide technical mentorship and scientific guidance to junior scientists, helping raise the overall bar of assay development rigor and execution.• Communicate complex analytical concepts and results clearly to both computational and non‑computational stakeholders, including senior leadership.Who You Are:REQUIRED EXPERIENCE:• Ph.D. in Bioinformatics, Computational Biology, Genomics, Biostatistics, or a closely related quantitative field. (or M.Sc. plus 3 additional years industry experience).• Minimum 6 years of total relevant experience in biotech, diagnostics, or regulated healthcare environments.• Demonstrated experience in NGS‑based assay development for clinical diagnostics. Hands‑on experience with ctDNA‑based MRD assays, including personalized or tumor‑informed approaches.• Strong programming skills in Python, with experience developing reproducible, production‑grade analysis pipelines, including experience with SDLC best practices.• Proven experience working in design‑controlled, regulated environments (CAP/CLIA LDT, IVD, or equivalent).• Proficiency in development of novel bioinformatics methodologies, and algorithms development, including benchmarking of computational methods.• Track record of working with wet lab scientists on iterative experiment design, execution, analysis, and interpretation as a tightly integrated team.• Demonstrated record of technical and scientific ownership, and independent work.PREFERRED EXPERIENCE:• Experience developing and deploying bioinformatics workflows in AWS (e.g., EC2, S3, Step Functions, Batch, Lambda, etc.).• Strong understanding of germline and somatic mutation processes leading to complex variation and genome-wide biomarkers with potential clinical utility.• Working knowledge of R.• Experience with relational and non-relational database technologies is a plus.#LI-Onsite, #LI-Hybrid, or #LI-RemoteFor candidates based in our San Diego office, the salary (or hourly range is $170,000 - $187,000.For candidates based in our South San Francisco office, the salary or hourly range is $177,000 - $207,000.For candidates working remote (US), the salary or hourly range is $162,000 - $178,000The final salary offered to a successful candidate will be dependent on several facto
What you'll get after applying
Unlike traditional applications, you won't submit and wait in silence. Here's what you get immediately:
See what you did well — communication, experience, enthusiasm
Specific, actionable feedback on how to strengthen your interview skills
Personalized guides and resources to help you grow professionally
Common questions
How does Apply by Voice work?
Instead of filling out forms or uploading a resume, you have a 6-10 minute voice conversation with an AI interviewer. It asks about your experience, skills, and interest in the role — then gives you instant feedback.
What feedback do I get after applying?
You'll immediately see your strengths highlighted, specific areas for improvement, actionable tips to get better, and recommended resources to build your interview skills.
How long does the conversation take?
Most conversations take 6-10 minutes. It's a natural back-and-forth about your experience — much faster than filling out a traditional application.